Two Patients with Anti Glomerular Basement Membrane Antibody Nephritis Showing Poor Prognosis Despite Intensive Therapy.
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چکیده
منابع مشابه
Comparison of double filtration plasmapheresis with immunoadsorption therapy in patients with anti-glomerular basement membrane nephritis
BACKGROUND Double filtration plasmapheresis (DFPP) and (IA) are both used to clear antibody. However, the clinical efficacy and safety of DFPP in patients with anti-glomerular basement membrane (anti-GBM) disease are unclear. METHODS The 28 enrolled patients diagnosed serologically and pathologically with anti-GBM disease from 2003 to 2013 included 16 treated with DFPP and 12 with IA, with al...
متن کاملAnti-glomerular basement membrane antibodies.
Basement membranes form an anatomic barrier that contains connective tissue. They are composed of type IV collagen, laminin and proteoglycans. Anti-basement membrane antibodies bind to the non-collagen site of the α3 chain of type IV collagen. A group of renal diseases, pulmonary diseases and perhaps others affecting different organs have long been associated with the presence of antibodies dir...
متن کاملChapter 14: Anti-glomerular basement membrane antibody glomerulonephritis
14.1: Treatment of anti-GBM GN 14.1.1: We recommend initiating immunosuppression with cyclophosphamide and corticosteroids plus plasmapheresis (see Table 31) in all patients with anti-GBM GN except those who are dialysis-dependent at presentation and have 100% crescents in an adequate biopsy sample, and do not have pulmonary hemorrhage. (1B) 14.1.2: Start treatment for anti-GBM GN without delay...
متن کاملAnti-Glomerular Basement Membrane Disease.
Anti-glomerular basement membrane (anti-GBM) disease is a rare small vessel vasculitis that affects the capillary beds of the kidneys and lungs. It is an archetypic autoimmune disease, caused by the development of directly pathogenic autoantibodies targeting a well characterized autoantigen expressed in the basement membranes of these organs, although the inciting events that induce the autoimm...
متن کاملRecurrent Venous Thromboses and Anti-glomerular Basement Membrane Antibody
Letters RecuRRent venous thRomboses and anti-glomeRulaR basement membRane antibody editor, We wish to record an association between a severe thrombophilic state and the presence of anti-glomerular basement membrane (anti-GBM) antibody. Case Report: An active man aged 41 noticed chest pain, haemoptysis and dark urine after a two-week lecture course late in March 2004. On 18 April he developed he...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 2001
ISSN: 1343-2826,1881-1191
DOI: 10.2974/kmj.51.141